Initial Functional and Structural Analysis of Plant Mechanosensitive Channel MSL10
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چکیده
منابع مشابه
Arabidopsis MSL10 Has a Regulated Cell Death Signaling Activity That Is Separable from Its Mechanosensitive Ion Channel ActivityC W
Members of the MscS superfamily of mechanosensitive ion channels function as osmotic safety valves, releasing osmolytes under increased membrane tension. MscS homologs exhibit diverse topology and domain structure, and it has been proposed that themore complex members of the family might have novel regulatory mechanisms or molecular functions. Here, we present a study of MscS-Like (MSL)10 from ...
متن کاملArabidopsis MSL10 has a regulated cell death signaling activity that is separable from its mechanosensitive ion channel activity.
Members of the MscS superfamily of mechanosensitive ion channels function as osmotic safety valves, releasing osmolytes under increased membrane tension. MscS homologs exhibit diverse topology and domain structure, and it has been proposed that the more complex members of the family might have novel regulatory mechanisms or molecular functions. Here, we present a study of MscS-Like (MSL)10 from...
متن کاملMscS-Like10 is a stretch-activated ion channel from Arabidopsis thaliana with a preference for anions.
Like many other organisms, plants are capable of sensing and responding to mechanical stimuli such as touch, osmotic pressure, and gravity. One mechanism for the perception of force is the activation of mechanosensitive (or stretch-activated) ion channels, and a number of mechanosensitive channel activities have been described in plant membranes. Based on their homology to the bacterial mechano...
متن کاملFunctional Analysis of Conserved Motifs in the Mechanosensitive Channel Homolog MscS-Like2 from Arabidopsis thaliana
The Mechanosensitive channel of Small conductance (MscS) of Escherichia coli has become an excellent model system for the structural, biophysical, and functional study of mechanosensitive ion channels. MscS, a complex channel with multiple states, contributes to protection against lysis upon osmotic downshock. MscS homologs are widely and abundantly dispersed among the bacterial and plant linea...
متن کاملSingle-channel mechanosensitive currents.
Morris and Horn (1) describe ion channel activity, elicited by mechanical stimulation, in both membrane patches and in whole neurons from the snail Lymnaea stagnalis. In whole-cell recordings, mechanical stimulation did not elicit the large macroscopic mechanosensitive currents (IMs) that were anticipated from studies of single mechanosensitive (MS) channels in membrane patches. These negative ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2014
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2013.11.4143